Before the Tumor (Continued)

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Medicine · Hospitals · Artificial Intelligence · health

A CT hits the server in Sacramento and, before a human sees it, software pings a neurologist’s phone: possible large-vessel stroke. “Time is a major determining factor in outcomes… the AI will help to prioritize cases,” says Dr. Kwan Ng at UC Davis.⁵ “Being able to make decisions quickly… ensures the best care.”

The point isn’t magic; it’s minutes. The FDA now says more than a thousand AI-enabled devices have cleared its pathways—a wave with radiology still in the engine room.¹²

Primary care is getting its own shortcuts. In 2018, the first autonomous diagnostic AI ever cleared by the FDA—IDx-DR—let a family clinic detect diabetic retinopathy in minutes, no ophthalmologist on site.⁶

Inside the endoscopy suite, a computer-aided system boxes tiny flickers of mucosa that slip past the human eye. In a randomized trial, adenoma detection jumped from ~40% to ~55% without lengthening the exam.⁷

On the pathology bench, Paige Prostate became the first FDA-authorized AI in digital pathology, flagging coordinates on whole-slide biopsy images so the pathologist’s eye goes straight to the likeliest trouble.⁸

Reality check. When auditors cracked open a widely used sepsis-prediction model embedded in EHRs, the system missed most cases and flooded clinicians with false alarms—triage upside down.⁹

And bias isn’t a metaphor. One hospital algorithm used cost as a proxy for need; because Black patients historically receive less costly care, the math quietly offered them less help.¹⁰

There are flameouts, too. IBM’s vaunted Watson for Oncology recommended “unsafe and incorrect” treatments, forcing a retreat to humbler goals.¹¹

Still, some bets age well. In 2020, an MIT–McMaster team used deep learning to surface an antibiotic, halicin, that killed drug-resistant pathogens in mice—a hint that AI might not only read biology but write it.¹³

If you want the human end of all this, it is as small as a woman in Sussex who got the all-clear from two radiologists—and then an AI extra reader found what eyes had missed. “I just feel so lucky,” said Sheila Tooth after a quick surgery and no chemo.¹⁴

Back in Worcester, the IV bags are still amber in the late-day light. Nancy watches hers climb and empties the last of her tea. The future is not a promise; it’s a nudge. When it works, what AI buys you is time—and the chance to spend it.

Chicago-Style Numbered Bibliography

1. Yala, Adam, et al. “Multi-Institutional Validation of a Mammography-Based Breast Cancer Risk Model.” Journal of Clinical Oncology 40, no.33 (2022): 3850–60. https://doi.org/10.1200/JCO.21.01337. A large external validation showing Mirai’s 1–5-year risk prediction held across seven health systems with C-indices ~0.75–0.84.

2. MIT Jameel Clinic. “Mirai.” Accessed October 2, 2025. https://jclinic.mit.edu/mirai/. Public page reporting Mirai’s scale (2M+ mammograms;72 hospitals;22 countries) and intended clinical use.

3. National Academy of Medicine. “Can AI Predict Breast Cancer? How a Scientist’s Personal Journey Led to an AI Model.” June 12, 2025. https://nam.edu/news-and-insights/can-ai-predict-breast-cancer/.

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